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Can at-home DNA tests predict how you’ll respond to your medications?

Published Sat, 22 Feb 2025 11:48:57 GMT

(The Conversation) - Have you ever wondered why certain medications don’t seem to work as well for you as they do for others? This variability in drug response is what pharmacogenomic testing hopes to explain by looking at the genes within your DNA.Pharmacogenomics, or PGx, is the study of how genes affect your response to medications. Genes are segments of DNA that serve as an instruction manual for cells to make proteins. Some of these proteins break down or transport certain medications through the body. Others are proteins that medications target to generate a desired effect.As pharmacists who see patients who have stopped multiple medications because of side effects or ineffectiveness, we believe pharmacogenomic testing has the potential to help guide health care professionals to more precise dosing and prescribing.How do PGx tests work?PGx tests look for variations within the genes of your DNA to predict drug response. For instance, the ...

At least one injured early Sunday in a shooting at a White Bear Lake sports bar

Published Sat, 22 Feb 2025 11:48:57 GMT

A man suffered a “very minor injury” during a shooting early Sunday in the parking lot of a White Bear Lake sports bar, authorities said.Officers found the man shortly before 1 a.m. at Original Doc’s Landing, 3200 White Bear Ave. N., according to Police Chief Dale Hager.The victim was treated at the scene.Another person may have suffered minor injuries, said Hager, but he described the shooting as an “isolated incident between two” people.“We don’t believe there is any known danger to the public,” he stressed.Related ArticlesCrime & Public Safety | 3 men dead, another in critical condition following shooting, stabbing at Roseville home Crime & Public Safety | Suspected car thief crashes into Grand Avenue pizza parlor, rams sheriff’s vehicle Crime & Public Safety | Jury finds Oakdale man guilty in Woodbury grad party shooting that killed Maplewood teen Crime & Public ...

Wild counting on bigger, stronger Marco Rossi

Published Sat, 22 Feb 2025 11:48:57 GMT

Marco Rossi has made the Wild roster out of camp before, last season, in fact, after earning a goal and five assists in just the preseason games. But it didn’t stick, and he found himself back in Iowa after 19 games.That won’t do this season for either Rossi or the Wild.“We’re looking for Marco Rossi to make our hockey club and be an impact player with the Minnesota Wild,” head coach Dean Evason said this week.The Wild are cap-strapped and high on the No. 9 overall pick in the 2020 draft, and Rossi is anxious to find a home in the NHL after last season’s setback and a serious bout with myocarditis that essentially wiped out his first season of professional hockey.It’s almost hard to believe he’s still only 22 years old.“I want to make the team and just want to show that I’ve improved over the last few years, and that I gained confidence and that I know what to do,” Rossi said as the Wild started training camp last week at TRIA Rink in downtown St. Paul.To that end, the Austria nativ...

Business People: U.S. Bank expands into health care banking services

Published Sat, 22 Feb 2025 11:48:57 GMT

OF NOTEJoe PersichettiU.S. Bank, Minneapolis, announced Joe Persichetti has been named head of its new Healthcare Business Banking, a cross-business initiative to serve health care practices with up to $25 million in annual revenue.FINANCIAL SERVICESPiper Sandler Cos., a Minneapolis-based national investment bank, announced that Tim Carter, chief financial officer, will retire in the first quarter of 2024. Kate Clune has been selected to succeed him. Previously, Clune spent 16 years at Morgan Stanley.GOVERNMENTThe office of Minnesota Attorney General Keith Ellison announced the following staff changes: Jerome Rankine becomes senior communications advisor; Brian Evans named press secretary; executive assistant Alex Boutrous also joins the communications team, and former Outreach Coordinator Keaon Dousti named assistant attorney general. … The Minnesota Department of Employment and Economic Development announced the appointment of Greg Norfleet as director of the state’s P...

Three $50K winning lottery tickets sold in Capital Region

Published Sat, 22 Feb 2025 11:48:57 GMT

ALBANY, N.Y. (NEWS10) -- Three third-prize winning Powerball tickets from the September 23 drawing were sold in the Capital Region. The tickets were purchased in Albany, Troy and Clifton Park. Get the latest news, weather, sports and entertainment delivered right to your inbox! The winning Powerball numbers drawn on Saturday were 1, 12, 20, 33, 66 and red Powerball 21. The third-prize tickets are each worth $50,000, and were sold at the following locations: Wolf Road Mobil - 88 Wolf Road in AlbanyCumberland Farms #1585 - 505 Campbell Avenue in TroyStewart's Shops #127 - 454 Route 146 in Clifton ParkThe Powerball drawing is televised every Monday, Wednesday and Saturday at 10:59 p.m. The New York Lottery contributed $3.7 billion in the 2022-2023 fiscal year toward supporting education in the state. Powerball jackpot now 4th-largest: When is your next chance to win? New Yorkers struggling with a gambling addiction, or who know someone that is, can find help at NYProble...

WATCH: Dolphins’ Tua Tagovailoa’s no-look touchdown pass to De’Von Achane against Broncos

Published Sat, 22 Feb 2025 11:48:57 GMT

TUA NO-LOOK SHOVEL PASS TD: #DENvsMIA on CBS: Stream on #NFLPlus https://t.co/UQdQ05hqXN pic.twitter.com/8IYZX0evXg— NFL (@NFL) September 24, 2023Related ArticlesDenver Broncos | Dolphins 21, Broncos 7: Tua Tagovailoa finds De’Von Achane for TD with no-look shovel pass Denver Broncos | Broncos Journal: OLBs must show they can stop run consistently, or they’ll keep getting picked on Denver Broncos | Kickin’ It with Kiz: Where can the crazy-rich Waltons get a $4.65 billion refund for these broken Broncos? Denver Broncos | Broncos safety Kareem Jackson fined after high hit in loss to Commanders Denver Broncos | NFL picks: Dallas’ roaring start, the AFC West’s offensive defenses and a big game in Detroit That was nifty.Early in the second quarter against the Broncos, Miami quarterback Tua Tagovailoa connected with De’Von Achane for a 4-yard, no-look shovel pass that ...

Denver weather: Seasonal temperatures, sunny skies, and light winds before heat returns

Published Sat, 22 Feb 2025 11:48:57 GMT

Fall weather continues in Denver Sunday with seasonal temperatures, sunny skies and light winds, according to the National Weather Service.A beautiful late September Sunday. Sunny skies, seasonal temperatures, and light winds. Enjoy! #COwx pic.twitter.com/d7bbRtMJm4— NWS Boulder (@NWSBoulder) September 24, 2023Temperatures in Denver will peak at 78 degrees Sunday, before heading back up in the mid- to high-80s the rest of the week.Overnight, city temperatures will drop down to 49 degrees, with areas in other parts of the state reaching as low as 10 degrees, NWS forecasters said.According to the NWS, sunny days and clear nights are expected to continue throughout the week.Forecast sky conditions next 5+ days. pic.twitter.com/6DaBdhVWm8— NWS Boulder (@NWSBoulder) September 23, 2023With both temperatures and weather conditions holding stable throughout the week, the dry spell will continue with no rainfall or flood threat, forecasters said.Get more Colorado news by signin...

Dolphins 21, Broncos 7: Tua Tagovailoa finds De’Von Achane for TD with no-look shovel pass

Published Sat, 22 Feb 2025 11:48:57 GMT

Can the Broncos break their slow 0-2 start and win their first game in the Sean Payton era? Stick here for live updates and analysis as Denver takes on the Dolphins at Hard Rock Stadium in Miami Gardens, Fla.Live updatesSecond-quarter updatesHUGE pass (11:54 a.m.): Russell Wilson connected with Marvin Mims Jr. for a huge 38-yard reception. Denver’s on first-and-goal at the Miami 10. — Joe NguyenTough catch by the rook. @marvindmims | : CBS or @paramountplus pic.twitter.com/5NBw5HbXjY— Denver Broncos (@Broncos) September 24, 2023As bad as the Broncos defense has looked, the Broncos offense is the exact opposite. Fantastic run from Javonte Williams. And then big play Marvin Mims Jr. emerges again. Broncos have second-and-goal at the Miami 10. — Matt SchubertNo-look pass (11:47 a.m.): That was nifty. Tua Tagovailoa did a no-look shovel pass to De’Von Achane for a 4-yard touchdown. Miami 21, Denver 7 with 10:16 to go in the second. — Joe NguyenTUA NO...

Smoke advisory issued for Los Angeles area due to NorCal wildfires

Published Sat, 22 Feb 2025 11:48:57 GMT

Wildfires burning in Northern California are having a significant impact on air quality in the Los Angeles metro area. According to the South Coast AQMD, smoke from the fires is currently being blown towards the South Coast air basin, causing elevated fine particulate matter (PM2.5) levels throughout the region. The impacts of the smoke are expected to last through the end of the day Sunday, officials said. PM2.5 levels may approach or exceed “Unhealthy for Sensitive Groups” levels at times, and the highest particulate levels are forecast for Sunday morning and into the afternoon. The air quality index as of 7:35 a.m. on Sept. 24, 2023. (KTLA)Areas further away from the coast are expected to see the worst air quality in the region this weekend.“Even if you don’t smell smoke, there may be smoke in your area,” the South Coast AQMD said in a statement.  Winning $5.4 million Powerball ticket sold in Southern California Actions SoCal residents can take during p...

My AP top-25 ballot: Georgia is No. 1, followed by FSU, as Washington State jumps USC

Published Sat, 22 Feb 2025 11:48:57 GMT

Ballot submitted to the Associated Press on Saturday night …Let’s cut to the issue that’s sure to elicit significant reaction: Yes, I ranked Washington State above USC. The Cougars are No. 11 on the ballot, one spot above the Trojans.And honestly, it took about a nanosecond to reach that conclusion.Before we compare and contrast, note that their current positions represent significant changes from the ballot submitted a week ago, when USC was No. 7, nine spots ahead of the Cougars.I jumped Penn State, Utah, Oregon and WSU over the Trojans after all four beat ranked teams and USC struggled with Arizona State. (Notre Dame also jumped USC after losing on the final play to Ohio State.)In the two-team ballot showdown, the Cougars (4-0) have been more impressive against a far stronger schedule.In fact, the only reason to rank USC (4-0) ahead of WSU at this point is preseason hype and/or brand bias. Because the resumes aren’t comparable.USC’s opponents (Nevada...